Critical Role of Cys168 in Noggin Protein's Biological Function
نویسندگان
چکیده
منابع مشابه
Critical role of Cys168 in noggin protein's biological function.
Previous studies have indicated that noggin exerts its neural inducing effect by binding and antagonizing bone morphogenetic protein 4 (BMP4). In order to further clarify the relationship between the structure and the function of noggin, and elucidate the possible mechanism responsible for noggin-BMP4 interaction, we generated three noggin mutants, C168S, C174S and C197S, by using a site-direct...
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ژورنال
عنوان ژورنال: Acta Biochimica et Biophysica Sinica
سال: 2005
ISSN: 1745-7270
DOI: 10.1093/abbs/37.3.181